According to Rober H. Lutig, professor of pediatrics and member of the Society of Endocrinology Obesity Task Force: "It is not our hormone of obesity, it is our hormone of hunger." It is a protein that is made in fat cells, circulates in the bloodstream, and goes to the brain. "It is the way your fat cells tell your brain that your power thermostat is fine." "It tells your brain that it has enough energy stored in its fat cells to participate in relatively expensive and normal metabolic processes," he says. In other words, when your leptin level is above the set threshold, your brain detects that you have enough energy, which means you can burn energy at a normal rate, eat food in a normal amount, exercise at a normal rate "

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Samuel Garcia 30 days ago

The importance of leptin in energy balance is illustrated by the extreme obese phenotype induced by leptin deficiency, and by the dramatic reduction in food intake and body weight that occurs upon treatment of this condition with leptin according to While leptin levels are closely matched to body adiposity at steady state, negative energy balance produces a fall in leptin levels that is more rapid than the change in body adiposity. Preventing this fall is sufficient to attenuate many of the physiological events associated with negative energy balance, and it is widely agreed that leptin is a critical signal of weight loss.